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Inflammasomes are intracellular multi-protein complexes whose accumulation causes the production of pro-inflammatory cytokines such as IL-1 and IL-6

These pain-relieving effects are blocked by drugs that affect norepinephrine, but not serotonin, suggesting that the pain relief works through adrenergic pathways (9)

This study also showed that levels of choline intake were inversely associated with homocysteine concentrations in the blood

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